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A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 348(20), 1953–1966. A. (2006). Early days: genomics and human responses to infection. Curr Opin Microbiol 9(3), 312–319. MalariaGen. (2009). , & Kampmann, B. (2008). Paediatric tuberculosis. Lancet Infect Dis 8(8), 498–510. W. (2004). Human genes that limit AIDS. Nat Genet 36(6), 565–574. A. et al. (2004). A novel and accurate diagnostic test for human African trypanosomiasis. Lancet 363(9418), 1358–1363. H. (2003).

Ciprofloxacin achieves rather poor CSF drug levels and is best not used in isolation. , 2002). Joint infections often involve the shoulder. This occurs especially in toddlers who are carried on their mothers’ backs and are swung into position by the mother grasping the upper arm and pivoting the child’s body weight on the shoulder joint. Minor local trauma may lead to seeding of NTS in the presence of a low-grade bacteremia (Molyneux and French, 1982). Joint infections require antibiotic therapy and surgical intervention.

1983). Norton et al. , 2004). , 2006). In another study from Mulago, Uganda, 22% of 134 malnourished children aged 6–59 months, 44% of whom were HIV infected, had a bacteremia. More than 70% were caused by Gram-negative bacteria, of which 67% were either salmonellae or E. coli. Hypoglycemia was a strong predictor of bacteremia. , 2002). An HIV-infected adult with a CD4 count of less than 200/ml is 48 times more likely to have invasive NTS disease than an uninfected adult (Gordon, 2008). , 1996).

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